Enhanced solubility protein expression strain

  • FOMO-21 is a derivative of the standard E. coli protein expression strain BL21(DE3), which contains a single Function Generator™ gene conferring increased protein solubility

  • FOMO-21 enables soluble expression of insoluble proteins

  • Suitable for expression of difficult target proteins including insoluble therapeutic targets, mammalian membrane proteins, enzymes discovered from metagenomic sequences


High-solubility Primordial Genetics strain FOMO-21 compared with the industry standard strain BL21(DE3) for percentage of soluble protein
1-11: Insoluble mammalian and plant proteins
12: Human Pro-Insulin
C: Control soluble protein

FOMO-21 is available for evaluation or licensing; please contact if interested.